Originally posted by vintner
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In your case, you should definitely keep your blood pressure controlled, be on a daily aspirin, and keep your cholesterol under control. As far as specific medications, a diuretic, an ACE inhibitor, and beta blocker would be what I'd recommend for blood pressure control first. You should be on a statin for cholesterol. This should be checked at least once a year as should your liver enzymes to make sure that you're tolerating it. You should have an EKG test done probably every five years or so. You should also DEFINITELY exercise nearly every day on a regular basis. If you get chest pains, short of breath, etc. then you should definitley have a stress test. If you're in poor shape, it may be a good idea as well. The gold standard in diagnosing heart disease is still a cardiac cath, but there's just under a 1% chance of having a serious complication from that, so the stress test usually comes first. You could consider getting a coronary calcium score as well (but not a full body scan, IMO), although the studies really haven't settled out as to where these should fit into the picture. I personally don't use them because the research isn't done yet. If you did get one done and your score was high, then I'd probably recommend additional testing to see if you would benefit from intervention. Another test that could be considered (but that I generally don't recommend) would be a high sensitivity CRP to see if your risk truly is a lot greater. Given your family history, I don't really think that this test is needed.
Finally, if you smoke you should stop, yesterday. If you've ever smoked and you're at least 65, you should get a screening ultrasound for aortic aneurysm. You should ask you doctor to also screen you for diabetes occasionally and to make sure that you have pulses in your feet as these can also be a sign of vascular disease.
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