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When is the best time of the year to vacation in Panama? There are actually two different seasons, a dry season which starts mid-December and lasts to mid-April and a rainy season which starts from mid-April to December. On the Caribbean coast of Panama, it seems to rain all the time, but less so in February to March, September to October. Days are generally hot throughout the year, with an average of 32 degrees Celsius, (90 degrees Fahrenheit to approximately 22 degrees Celsius (72 degrees Fahrenheit in the evenings. During the rainy season, the humidity is quite high. If you are traveling to the mountains, it is cooler with a temperature ranging from about 10 - 18 degrees Celsius (50 - 64 degrees Fahrenheit throughout the year.
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